Author

Mariella Franker

2 Publications

4. July 2016 | DOI: 10.17160/josha.3.3.198

Assembly and disassembly of Rad51 filaments on single-stranded DNA: A novel assay to study the dynamics of protein-ssDNA interactions at the single-molecule level

Mariella Franker

Eukaryotic recombinase protein Rad51 is the key player in homologous recombination, an essential DNA repair mechanism used for the repair of double-strand breaks. Double-strand breaks can lead to chromosome fragmentation…

1,599

3,804

Homologous recombination: Single-molecule experiments and their lessons for the in vivo situation

Mariella Franker

Homologous recombination is an essential DNA repair mechanism in both prokaryotes and eukaryotes. It especially plays an important role in the repair of broken or stalled replication forks and is…

1,645

3,909