master thesis – Josha Journal

2. August 2021 | DOI: 10.17160/josha.8.3.771

Evaluation of Chloroquine and Hydroxychloroquine Efficacy on Chemotherapy Treatment in triple negative Breast Cancer by continuous live Cell Imaging

Triple negative breast cancer is heterogeneous type of breast cancer which, due to its high proliferation, aggressiveness, rapid progression and poor prognosis, is still a challenge to treat. These characteristics,…

1,639

2,311

Characterization of the AZF region of the Y chromosome in Native American haplogroup Q

E

Evguenia Alechine, Werner Schempp, Daniel Corach

University of Buenos Aires

The Y chromosome is a genomic niche for genes involved in male gamete production. The existence of an azoospermia factor (AZF) in its long arm is a key genetic determinant…

1,970

4,947

Assembly and disassembly of Rad51 filaments on single-stranded DNA: A novel assay to study the dynamics of protein-ssDNA interactions at the single-molecule level

M

Mariella Franker

Eukaryotic recombinase protein Rad51 is the key player in homologous recombination, an essential DNA repair mechanism used for the repair of double-strand breaks. Double-strand breaks can lead to chromosome fragmentation…

1,607

3,804