carcinogenesis – Josha Journal

29. May 2020 | DOI: 10.17160/josha.7.3.677

Alpha and Omega: from the Sagrada Familia to Placenta and Cancer

M

Miguel Hernández-Bronchud

GCCC 360 Oncology Genesis Care Corachán

The links between architecture and science are as old as these human achievements. But modern scientific thought and methods are much more recent than architecture. In 1660, Christopher Wren gave…

2,897

3,870

Read more PDF

Towards Simulating Carcinogenesis: Modeling and Simulating Carcinogenesis, Hematopoietic Tissue Homeostasis and Leukemogenesis

Artificial Intelligence, Modeling and Simulation

6. November 2016 | DOI: 10.17160/josha.3.7.253

Towards Simulating Carcinogenesis: Modeling and Simulating Carcinogenesis, Hematopoietic Tissue Homeostasis and Leukemogenesis

J

Jenny Groten, Maximilian Georg, Oliver Worm, Christoph Borner, Roland Mertelsmann

Institut für Molekulare Medizin und Zellforschung

The previously identified cancer hallmarks (Groten et al. 2016, DOI: 10.17160/josha.3.7.252 ) were described by mathematical algorithms. Subsequently, a computational simulation of carcinogenesis has been developed. In the next step,…

1,843

4,974

Read more PDF

Understanding and Controlling Cancer: The Hallmark Concept Revisited – Chance, Evolution and Entropy

Medicine

6. November 2016 | DOI: 10.17160/josha.3.7.252

Understanding and Controlling Cancer: The Hallmark Concept Revisited – Chance, Evolution and Entropy

J

Jenny Groten, Christoph Borner, Roland Mertelsmann

Institut für Molekulare Medizin und Zellforschung

The overall aim of this investigation was to identify the fundamental phenotypic traits of a cancer cell to develop an “in silico” simulation model and, vice versa redefine the identified…

1,963

5,816

Read more PDF

Hepatocellular alterations and dysregulation of oncogenic pathways in the liver of transgenic mice overexpressing growth hormone

Medicine

20. May 2015 | DOI: 10.17160/josha.2.4.40

Hepatocellular alterations and dysregulation of oncogenic pathways in the liver of transgenic mice overexpressing growth hormone

T

Thomas Freund

Uniklinik Freiburg, IMBS

The use of growth hormone has risen in the last years. Apart from its interactions in growth and metabolism, its use has been approved in different clinical conditions which do…

1,545

3,784

Read more PDF